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TRANSFORMING GROWTH FACTOR
BETA (BOVINE)

PRODUCT DESCRIPTION

​Transforming Growth Factor Beta (TGF-β) acts as a potent multifunctional cytokine involved in a diverse range of biological processes

Natively, TGF-β is secreted in a latent form complexed with two other polypeptides, the latent TGF-β binding protein and the latency-associated peptide. The cytokine is then activated by the proteolytic cleavage of these two polypeptides, releasing the mature 112 amino acid TGF-β. It lends itself to muscle repair, embryogenesis, wound healing, connective tissue development, cell growth and differentiation, cell proliferation and apoptosis, and contributes to the regulation of immune responses.

​Immobazyme's recombinant TGF-β is produced in the E. coli and purified using immobilized metal ion affinity chromatography.

TGF-β PRODUCT INFORMATION

Grade

Food-grade, Allergen-free

Amount

100 μg per vial

Molecular Weight

65.5 kDa (with fusion protein)

Production System

E. coli

Protein Information

TGF-β is a monomeric fusion peptide with enhanced stability and solubility

Purification Method

Sequential chromatography (IMAC, desalting and heparin)

Filtration

Filtered through a 0.22 μm sterile filter

Sterility

Sterile

Mycoplasma

Absent

Form

Lyophilized powder

Purity

>80%

Storage Condition

Lyophilized sample is transported at ambient temperature. For extended shelf life, store at -20°C before and after reconstitution.

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