TRANSFORMING GROWTH FACTOR
BETA (BOVINE)
PRODUCT DESCRIPTION
Transforming Growth Factor Beta (TGF-β) acts as a potent multifunctional cytokine involved in a diverse range of biological processes
Natively, TGF-β is secreted in a latent form complexed with two other polypeptides, the latent TGF-β binding protein and the latency-associated peptide. The cytokine is then activated by the proteolytic cleavage of these two polypeptides, releasing the mature 112 amino acid TGF-β. It lends itself to muscle repair, embryogenesis, wound healing, connective tissue development, cell growth and differentiation, cell proliferation and apoptosis, and contributes to the regulation of immune responses.
Immobazyme's recombinant TGF-β is produced in the E. coli and purified using immobilized metal ion affinity chromatography.
TGF-β PRODUCT INFORMATION
Grade
Food-grade, Allergen-free
Amount
100 μg per vial
Molecular Weight
65.5 kDa (with fusion protein)
Production System
E. coli
Protein Information
TGF-β is a monomeric fusion peptide with enhanced stability and solubility
Purification Method
Sequential chromatography (IMAC, desalting and heparin)
Filtration
Filtered through a 0.22 μm sterile filter
Sterility
Sterile
Mycoplasma
Absent
Form
Lyophilized powder
Purity
>80%
Storage Condition
Lyophilized sample is transported at ambient temperature. For extended shelf life, store at -20°C before and after reconstitution.
